An in-depth comparison of our favorite topical analgesics (topical pain relief gels) CryoDerm vs BioFreeze. Learn which one is best for you today!
A lot of our patients utilize at-home pain relief methods between treatments – and by far the most popular product we sell? Pain relief gel. Not only is it inexpensive at $20 a bottle but topical analgesics also provide fast relief for around 3 hours at a time. (Plus, you can keep a spare bottle in your car or bag for on-the-go relief.)
The two pain relief gels we love and highly recommend are CryoDerm and Biofreeze! However, as the two have different formulas and properties, we decided to write up a detailed comparison post to help inform your choice.
First off: what is a cold-therapy topical analgesic?
Topical analgesic is a fancy way of saying: pain relief gel. Both Biofreeze and CryoDerm utilise cold therapy treatment, so they act as cooling agents when applied to the painful area.
Traditional thinking is that the pain-relieving mechanism of action of menthol – the active ingredient in all of these topicals results from a counter-irritant effect. Simply put, a counter-irritant has an effect of overriding noxious pain signals traveling to the brain through a process modulated between pain-transmitting and non-pain transmitting neurons.Source: News.Meyerdc.com
How do cold-therapy pain relief gels work?
It’s a clever way of tricking your body – and has proven to be very effective!
Cryoderm vs Biofreeze Feature Comparison
Biofreeze’s menthol concentration is 4%, while CryoDerm’s is 10%
Menthol is the key ingredient in counter-irritants and a higher concentration can mean stronger pain relief. CryoDerm’s formula has a concentration almost double that of Biofreeze, clocking in at 10%.
While this can mean faster results, products with a higher menthol concentration are more likely to irritate your skin – so people with extremely sensitive skin may want to keep that in mind.
Reviewers have found Biofreeze to have the most immediate cooling effect – but CryoDerm produces the “deepest sensation of cold”.
In a DC Aligned survey, 6 out of 10 patients who were asked to compare the products said that Biofreeze produced the most immediate cold sensation. (3 out of 10 said CryoDerm and one chose Rocksauce Chill.) That being said, 5 of the sample advised that CryoDerm produced the deepest sensation of cold, compared to only 2 who chose Biofreeze.
When asked abut the strength and duration of the treatments, here are how the patients answered:
10 out of 10 advised Biofreeze stays relatively the same in terms of cold and peneration. Quotes DC Aligned used were “it’s cold from the minute you put it on and stays that way for up to two hours” and “it also never changed in depth of cold”.
Comparatively, 10 out of 10 patients agreed that CryoDerm’s pain relief treatment changed and deepened over time. Each patient stated that CryoDerm didn’t have the initial cold shock that comes with Biofreeze – but, after 5-10 minutes, the cold penetrated deeper.
Something to note is that reviewers found CryoDerm’s formula to be long-lasting. While Biofreeze normally weakens after two hours, one tester felt that CryoDerm stayed relatively cold for up to 5 hours!
Although on paper CryoDerm performed better during this study for pain relief, patients in this survey preferred Biofreeze
When you read these results, you’d likely think most people preferred CryoDerm. Deeper penetration and longer lasting pain relief – what’s not to love? However, the results of this in-house survey say differently!
When asked for their preference between 3 topical analgesics, 6 out of 10 patients preferred Biofreeze. They stated that if they wanted to use a topical pain relief gel, they wanted the cold to be as instant as possible and consistent.
3 out of 10 patients preferred CryoDerm. The comments these patients made were that they liked the more subtle cold introduction and a deeper more penetrating feeling that Cryoderm provides. They also stated that they felt Cryoderm lasted longer when applied.
To conclude, the winner is . . .
Whichever product sounds best to you! As we’ve covered, both are highly effective at relieving pain – and, if you purchase from our clinic, each will only set you back $20. Hopefully, this article allowed you some insight into which of these at-home pain relief gels might suit your needs best.